{"id":8275,"date":"2021-10-13T12:07:28","date_gmt":"2021-10-13T10:07:28","guid":{"rendered":"http:\/\/dev1.jcverbanck.com\/cosmetic-product\/"},"modified":"2022-01-19T12:58:15","modified_gmt":"2022-01-19T11:58:15","slug":"cosmetic-product","status":"publish","type":"page","link":"http:\/\/preditox.fr\/en\/cosmetic-product\/","title":{"rendered":"Cosmetic product"},"content":{"rendered":"

[vc_row css=”.vc_custom_1633360548421{padding-top: 50px !important;padding-bottom: 35px !important;}”][vc_column ts_responsive_css=”61491674|colbreak_no|||||||||colbreak_no|||||||||colbreak_no|||||||0|||colbreak_no|||||||||”][vc_column_text]<\/p>\n

The study of the toxic and carcinogenic potential of a compound is an integral part of a good development process and ensures the quality of your cosmetic products. Anticipating these analyzes allows you to better control your R&D planning and to be able to select the most promising candidate products early and efficiently.<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row equal_height=”yes” css=”.vc_custom_1633360424100{padding-top: 0px !important;}”][vc_column ts_bgcolor=”skincolor” ts_col_bg_expand=”left” width=”1\/2″ css=”.vc_custom_1633364475376{margin-top: 120px !important;padding-top: 35px !important;padding-right: 40px !important;padding-left: 25px !important;}” ts_responsive_css=”71891908|colbreak_no|||||||||colbreak_no|||||||||colbreak_no|0|||||||||colbreak_no|||||||||”][vc_custom_heading text=”Animal testing prohibited in Europe” font_container=”tag:h2|font_size:40px|text_align:left|color:%23ffffff|line_height:50px” google_fonts=”font_family:Roboto%20Condensed%3A300%2C300italic%2Cregular%2Citalic%2C700%2C700italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1634202451516{margin-bottom: 15px !important;}”][vc_column_text]<\/p>\n

Only alternative methods are legally permitted for the testing of cosmetic products and their ingredients, as animal testing is prohibited in Europe (Article 18 of Regulation No 1223\/2009 of the European Cosmetics Regulation).<\/p>\n

[\/vc_column_text][vc_column_text]<\/p>\n

In October 2018, the 10th revision of the Scientific Committee on Consumer Safety (CSSC) on testing cosmetic ingredients was adopted and now focuses on non-animal methodologies and strategies (SCCS \/1602\/18). A section on the weight of evidence (WoE) for genotoxicity testing has been included, and tests using \u03b3H2AX and pH3 biomarkers, such as our PrediScreen test, are cited to efficiently investigate the genotoxic potential of a cosmetic product or ingredient.<\/p>\n

[\/vc_column_text][\/vc_column][vc_column ts_col_bg_expand=”right” width=”1\/2″ css=”.vc_custom_1639076487485{background-image: url(http:\/\/preditox.fr\/wp-content\/uploads\/cosmetique-1-1.jpg?id=9107) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1633363580563{padding-bottom: 0px !important;}”][vc_column width=”1\/2″][vc_single_image image=”9112″ img_size=”large” alignment=”center”][\/vc_column][vc_column width=”1\/2″ css=”.vc_custom_1633361924005{padding-top: 30px !important;}”][vc_custom_heading text=”Genotoxicity assay” font_container=”tag:h2|font_size:38px|text_align:left” use_theme_fonts=”yes” css=”.vc_custom_1634202240761{margin-bottom: 20px !important;}”][vc_column_text]<\/p>\n

To meet your needs, PrediTox offers a complete and alternative genotoxicity test to the animal experiment, the PrediScreen assay (\u03b3H2AX\/pH3 assay), to evaluate the safety of your ingredients and finished cosmetic products.<\/p>\n

Our technique is designed to be fast and reliable, without any loss of sensitivity or specificity.<\/p>\n

[\/vc_column_text][vc_btn title=”More information” style=”flat” shape=”square” color=”primary” align=”left” link=”url:http%3A%2F%2Fpreditox.fr%2Fen%2Fservice%2Fgenotoxicity-assay%2F|title:Genotoxicity%20assay|”][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1634641837743{padding-bottom: 0px !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}”][vc_column ts_bgcolor=”skincolor” width=”1\/2″ css=”.vc_custom_1633363647428{padding-top: 50px !important;padding-right: 40px !important;padding-bottom: 50px !important;padding-left: 40px !important;}”][vc_custom_heading text=”Antioxidant effect” font_container=”tag:h2|font_size:38px|text_align:left|color:%23ffffff” use_theme_fonts=”yes” css=”.vc_custom_1634202256352{margin-bottom: 20px !important;}”][vc_column_text]<\/p>\n

On the skin, oxidation is a major phenomenon responsible for cellular aging because it damages the cells and contributes to their degeneration.<\/p>\n

In cosmetics, an antioxidant can help skin fight against free radicals, and limit premature cutaneous aging.<\/p>\n

In order to meet this demand, PrediTox offers you the PrediProtect test to study the antioxidant effect of your ingredients and finished cosmetics.<\/p>\n

[\/vc_column_text][vc_btn title=”More information” style=”flat” shape=”square” color=”white” align=”left” link=”url:http%3A%2F%2Fpreditox.fr%2Fen%2Fservice%2Fantioxidant-effect%2F|title:Genotoxicity%20assay|”][\/vc_column][vc_column width=”1\/2″][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1633364027280{padding-top: 0px !important;}” ts_responsive_css=”74064465|colbreak_no|||||||||colbreak_no|||||||||colbreak_yes||||||||||colbreak_no|||||||||”][vc_column width=”1\/4″ offset=”vc_hidden-sm vc_hidden-xs”][\/vc_column][vc_column width=”1\/4″ css=”.vc_custom_1637169193888{margin-top: -120px !important;margin-left: 30px !important;}” offset=”vc_hidden-sm vc_hidden-xs”]

\"\"<\/div><\/div>[\/vc_column][vc_column width=”1\/2″ css=”.vc_custom_1637169204455{padding-right: 40px !important;padding-left: 40px !important;}”][vc_custom_heading text=”DNA repair” font_container=”tag:h2|font_size:38px|text_align:left” use_theme_fonts=”yes” css=”.vc_custom_1634202275289{margin-bottom: 20px !important;}”][vc_column_text]<\/p>\n

Our cells are daily attacked by physical or chemical agents, which induce DNA damage that can lead to a process of carcinogenesis.<\/p>\n

Some compounds are able to act on these lesions by acting on the damage repair pathways and thus protect the DNA of our cells. This is the purpose of the PrediRepair assay.<\/p>\n

[\/vc_column_text][vc_btn title=”More information” style=”flat” shape=”square” color=”primary” align=”left” link=”url:http%3A%2F%2Fpreditox.fr%2Fen%2Fservice%2Fdna-repair%2F|title:Genotoxicity%20assay|”][\/vc_column][\/vc_row][vc_row css=”.vc_custom_1633364027280{padding-top: 0px !important;}” ts_responsive_css=”74064465|colbreak_no|||||||||colbreak_no|||||||||colbreak_yes||||||||||colbreak_no|||||||||”][vc_column width=”1\/2″ offset=”vc_hidden-lg vc_hidden-md”][vc_custom_heading text=”DNA repair” font_container=”tag:h2|font_size:38px|text_align:left” use_theme_fonts=”yes” css=”.vc_custom_1634202275289{margin-bottom: 20px !important;}”][vc_column_text]<\/p>\n

Our cells are daily attacked by physical or chemical agents, which induce DNA damage that can lead to a process of carcinogenesis.<\/p>\n

Some compounds are able to act on these lesions by acting on the damage repair pathways and thus protect the DNA of our cells. This is the purpose of the PrediRepair assay.<\/p>\n

[\/vc_column_text][vc_btn title=”More information” style=”flat” shape=”square” color=”primary” align=”left” link=”url:http%3A%2F%2Fpreditox.fr%2Fen%2Fservice%2Fdna-repair%2F|title:Genotoxicity%20assay|”][\/vc_column][vc_column width=”1\/2″ offset=”vc_hidden-lg vc_hidden-md”]

\"\"<\/div><\/div>[\/vc_column][\/vc_row][vc_row ts_bgcolor=”skincolor” full_width=”stretch_row” css=”.vc_custom_1639076642964{padding-top: 55px !important;padding-bottom: 30px !important;background-image: url(http:\/\/preditox.fr\/wp-content\/uploads\/banner-3.jpg?id=9129) !important;background-position: center !important;background-repeat: no-repeat !important;background-size: cover !important;}” el_class=”icon-box-blanc”][vc_column][vc_custom_heading text=”Protocol” font_container=”tag:h2|font_size:40px|text_align:center|color:%23ffffff” google_fonts=”font_family:Roboto%20Condensed%3A300%2C300italic%2Cregular%2Citalic%2C700%2C700italic|font_style:300%20light%20regular%3A300%3Anormal” css=”.vc_custom_1634202307352{margin-bottom: 15px !important;}”][vc_column_text]<\/p>\n

Characterizing the toxicity and carcinogenic potential of your<\/span> products and \/ or ingredients used in your formulations is of major interest<\/span>for human health<\/span>.<\/span> <\/span><\/p>\n

In order to help you in this process, PrediTox carries out tailor-made studies according to your<\/span> needs
\nand can offer you the following technical specifications<\/span> :<\/span><\/span><\/p>\n

[\/vc_column_text][vc_row_inner css=”.vc_custom_1637169387487{padding-top: 20px !important;}”][vc_column_inner width=”1\/2″ ts_responsive_css=”58918327|colbreak_no||||||||70px|colbreak_no|||||||||colbreak_no|||||||||3000|colbreak_no||||||||70px|”]\n\n

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Echantillons<\/h2>\n<\/div><\/div><\/div><\/div><\/div>\t\t\t
– raw materials and \/ or finished products
\n– powder or liquid
\n– small quantities : 10 mg or 1 mM<\/div>\t\t\t\t\t<\/div>\n\t<\/div>\t\n<\/div>\n\n[\/vc_column_inner][vc_column_inner width=”1\/2″ ts_responsive_css=”73543930|colbreak_no||||||||70px|colbreak_no|||||||||colbreak_no|||||||||3000px|colbreak_no||||||||70px|”]\n\n
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Lign\u00e9es cellulaires<\/h2>\n<\/div><\/div><\/div><\/div><\/div>\t\t\t
Wide choice of human cell lines available<\/div>\t\t\t\t\t<\/div>\n\t<\/div>\t\n<\/div>\n\n[\/vc_column_inner][\/vc_row_inner][vc_row_inner css=”.vc_custom_1637170075392{padding-top: 30px !important;}”][vc_column_inner width=”1\/2″ ts_responsive_css=”58918327|colbreak_no||||||||70px|colbreak_no|||||||||colbreak_no|||||||||3000|colbreak_no||||||||70px|”]\n\n
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Essais<\/h2>\n<\/div><\/div><\/div><\/div><\/div>\t\t\t
– preparation of a solution from your
\nproduct (DMSO, water, etc.)
\n– different concentrations and dilutions tested
\n– treatment time of your choice
\n– internal negative and positive controls
\n– at least biological triplicate<\/div>\t\t\t\t\t<\/div>\n\t<\/div>\t\n<\/div>\n\n[\/vc_column_inner][vc_column_inner width=”1\/2″ ts_responsive_css=”78103568|colbreak_no||||||||70px|colbreak_no|||||||||colbreak_no|||||||||3000px|colbreak_no||||||||70px|”]\n\n
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Expertise<\/h2>\n<\/div><\/div><\/div><\/div><\/div>\t\t\t
Complete confidential report including all raw results and their analyzes within 15 days.<\/div>\t\t\t\t\t<\/div>\n\t<\/div>\t\n<\/div>\n\n[\/vc_column_inner][\/vc_row_inner][vc_btn title=”More information” style=”flat” shape=”square” color=”white” align=”center” link=”url:http%3A%2F%2Fpreditox.fr%2Fen%2Fprotocol%2F|title:Genotoxicity%20assay|”][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row css=”.vc_custom_1633360548421{padding-top: 50px !important;padding-bottom: 35px !important;}”][vc_column ts_responsive_css=”61491674|colbreak_no|||||||||colbreak_no|||||||||colbreak_no|||||||0|||colbreak_no|||||||||”][vc_column_text] The study of the toxic and carcinogenic potential of a compound is an integral part of a good development process and ensures the quality of your cosmetic products. Anticipating these analyzes allows you to better control your R&D planning and to be able to select the most promising … Continue reading Cosmetic product<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-8275","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/pages\/8275","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/comments?post=8275"}],"version-history":[{"count":90,"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/pages\/8275\/revisions"}],"predecessor-version":[{"id":9573,"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/pages\/8275\/revisions\/9573"}],"wp:attachment":[{"href":"http:\/\/preditox.fr\/en\/wp-json\/wp\/v2\/media?parent=8275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}